Wednesday 6th June

09.20 – 11.00   Session 1: Drug Testing and Signal Transduction

1.1 (09.20 – 09:50) Invited Talk - Prof Charlie Keese

Title TBA

Applied biophysics, Troy, NJ, USA

1.2 (09:50 – 10.10) "Increased Throughput in GPCR Screening using Impedance Assays: Inspiration from Organ Studies"

J.A. Stolwijk, C. Kade, M. Skiba and J. Wegener

Universität Regensburg, Regensburg (Germany)

1.3 (10.10 – 10.30) "Chlorpromazine disrupts structural integrity of cell membranes in HepaRG cells and initiates a pro-inflammatory response"

K. Morgan1, N. Martucci2, A. Kozlowska1, W. Gamal3, F. Brzeszczynka1, K. Samuel4, P. Treskes1, P. Hayes1, L. Nelson1, P. Bagnaninchi2, J. Brzeszczynska1 and J. Plevris1

1 Hepatology Laboratory, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh; United Kingdom; 2 MRC Centre for Regenerative Medicine, 5 Little France Drive, Edinburgh EH16 4UU; 3 School of Electronic Engineering and Computer Science, Bangor University, Dean Street, Bangor, Gwynedd, LL57 1UT; 4 Scottish National Blood Transfusion Service, Advanced Therapeutics The Jack Copland Centre, 52 Research Avenue North, Edinburgh

1.4 (10.30 – 10.50) "Time-resolved Response Profiles of GPCR Activation: Combining Two Independent Impedance-Based Approaches"

C. Kade1, J. Stolwijk1, S. Michaelis2 and J. Wegener1,2

1 Universität Regensburg, Regensburg (Germany); 2 Fraunhofer EMFT, Division Cell-Based Sensors, Regensburg (Germany)